- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
LMK-235 induces the differentiation of odontoblasts in dental pulp cells. It plays an important role in the regeneration of dental tissue.
LMK235 is a histone deacetylase (HDAC) inhibitor with greater potency against HDAC4 and HDAC5 (IC50 = 11.9 and 4.2 nM, respectively) than other HDAC family members (IC50 values = HDAC1 320 nM, HDAC2 881 nM, HDAC6 55.7 nM, and HDAC8 1278 nM). LMK235 potentiates the cytotoxic effects of cisplatin, and sensitizes platinum-drug resistant tumor cell lines to cisplatin toxicity.
LMK235 is a histone deacetylase (HDAC) inhibitor; HDAC4- and HDAC5-preferring.
Features and Benefits
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | N(OCCCCCC(=O)NO)C(=O)c1cc(cc(c1)C)C |
| InChI | 1S/C15H22N2O4/c1-11-8-12(2)10-13(9-11)15(19)17-21-7-5-3-4-6-14(18)16-20/h8-10,20H,3-7H2,1-2H3,(H,16,18)(H,17,19) |
| InChI key | VRYZCEONIWEUAV-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
¥ 12156.68
-
询价
-
¥ 2019.57
-
¥ 1451.54
-
¥ 9207.92
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 1956.41
-
¥ 3152.47
-
询价
-
询价
-
¥ 3812.28
-
询价
-
¥ 1783.21
-
¥ 2277.64
-
¥ 10685.48
微信小程序
7X24小时在线咨询