- 商品介绍
- 规格参数
- 包装参数
Application
RK-682 has been used:
- as a positive control in high-performance liquid chromatography (HPLC)
- as a reference compound in high-performance liqiud chromatography (HPLC)
- as a pan-protein tyrosine phosphatase non-receptor type (PTPN) inhibitor to study its effects on the activated lymphocytes
Biochem/physiol Actions
RK-682 is a specific and noncompetitive inhibitor of protein tyrosine phosphatase; It inhibited dephosphorylation activity of CD45 and VHR with IC50 54 and 2.0 microM and 4.5 microM against PTP1B.
Specific and noncompetitive inhibitor of protein tyrosine phosphatase.
Features and Benefits
This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to tan |
| solubility | DMSO, heptane and xylene: ≥8 mg/mL |
| storage temp. | −20°C |
| SMILES string | CCCCCCCCCCCCCCCC(=O)C1=C(O)[C@@H](CO)OC1=O |
| InChI | 1S/C21H36O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(23)19-20(24)18(16-22)26-21(19)25/h18,22,24H,2-16H2,1H3/t18-/m1/s1 |
| InChI key | KZTSLHQKWLYYAC-GOSISDBHSA-N |
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¥ 12156.68
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¥ 1563.36
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¥ 5887.85
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¥ 5725.45
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¥ 4404.38
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¥ 1156.91
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¥ 1301.36
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¥ 1783.21
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