- 商品介绍
- 规格参数
- 包装参数
General description
PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN13 is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal-associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. PTPN13 binds to a negative regulatory domain in Fas that inhibits Fas-induced apoptosis.
Physical form
Supplied in 20mM MOPS, pH 7.5, 50mM NaCl, 10mM glutathione, 0.25mM DTT, 0.1mM PMSF, 30% glycerol.
Preparation Note
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
| recombinant | expressed in E. coli |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | 2040-2760 nmol/min·mg |
| mol wt | ~61 kDa |
| NCBI accession no. | NM_080683 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... PTPN13(5783) |
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¥ 1048.84
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¥ 503.76
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¥ 1669.50
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¥ 3317.36
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¥ 3408.16
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¥ 661.45
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¥ 968.94
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¥ 619.92
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¥ 656.88
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¥ 1101.77
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¥ 67162.32
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¥ 8072.66
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