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General description
Matrix metallopeptidase 15 (MMP-15) is encoded by the gene mapped to human chromosome l Iq22.2-22.3. The encoded protein belongs to the membrane-type matrix metalloproteinases (MT-MMPs).
Anti-MMP-15 Antibody detects endogenous levels of total MMP-15 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human MMP-15.
Immunogen Range: 611-660
Biochem/physiol Actions
Matrix metallopeptidase 15 (MMP-15) is implicated in the activation of pro-MMP-2 and pro-MMP-13. It is also facilitates tumor necrosis factor a processing. MMP-15 might promote various types of cancer progression, including non-small cell lung cancer (NSCLC). In addition, it also promotes gastric cancer (GC) invasion and metastasis. Thus, this protein can be used as a potent prognostic marker for GC patients.
Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 75 kDa |
| species reactivity | human, mouse |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:10000,western blot: 1:500-1:1000 |
| NCBI accession no. | P51511 |
| UniProt accession no. | P51511 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... MMP15(4324) |
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