Anti-Phospho-EIF4EBP1-T70 antibody produced in rabbit,100UL,SAB5700295-100UL,Sigma

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订货号 0BN4990
品牌型号 Sigma SAB5700295-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.


Immunogen

A synthetic phosphorylated peptide around T70 of human EIF4EBP1 (NP_004086.1).


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Level100
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 12
species reactivitymouse, human
concentration1.78 mg/ml
technique(s)western blot: 1:500-1:2000
UniProt accession no.Q13541
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pThr70)
Gene Informationhuman ... EIF4EBP1(1978)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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