ʟ-trans-Pyrrolidine-2,4-dicarboxylic acid,10MG,P7575-10MG,Sigma

销售价: ¥ 2991.77 / 件
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订货号 0BN0331
品牌型号 Sigma P7575-10MG
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最小订货量 1件
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产品介绍 Product Description

Application

L-trans-Pyrrolidine-2,4-dicarboxylic acid has been used:

  • as a glutamate transport inhibitor to test its impairing effect on glutamate-induced cell death in HT22 neuronal cells
  • as an analog of glutamate to test its effect on glutamate/glutamine-dependent acid resistance of E. coli and S. flexneri
  • as sodium glutamate (Na+/Glu) cotransporter inhibitor in myogenic cell line C2C12


Biochem/physiol Actions

L-trans-Pyrrolidine-2,4-dicarboxylic acid is a selective glutamate transporter inhibitor.


技术参数 Specifications
Quality Level100
assay≥98%
formpowder
SMILES stringOC(=O)[C@H]1CN[C@@H](C1)C(O)=O
InChI1S/C6H9NO4/c8-5(9)3-1-4(6(10)11)7-2-3/h3-4,7H,1-2H2,(H,8,9)(H,10,11)/t3-,4+/m1/s1
InChI keyNRSBQSJHFYZIPH-DMTCNVIQSA-N
Gene Informationrat ... Gria1(50592), Grik1(29559), Grin2a(24409), Slc1a2(29482), Slc1a3(29483)
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