Rat IL-1 β ELISA Kit，1KIT，RAB0278-1KT，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

The Rat IL-1 β ELSA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Rat IL-1β cell lysate and tissue lysate.

Immunogen

Recombinant Rat IL-1 β

Application

For research use only. Not for use in diagnostic procedures

Rat IL-1 Β ELISA Kit has been used to measure IL-1 Β levels .
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Pro-inflammatory cytokine IL-1 Β (IL1B), which is highly expressed on Β-adrenoreceptor in obese adipose tissues, is implicated in induction of uncoupling protein 1 (UCP1) expression via extracellular signal-regulated kinase (ERK) activation in adipocytes. Macrophage autophagy inhibits the production of inflammasome-dependent IL-1Β and thereby it plays a vital role in reducing acute toxin-induced liver injury and death. In rats, IL-1Β enhanced neurogenesis and plasticity of carotid bodies (CB) by triggering ERK1/2 activation. IL-1Β plays a vital role in alteration of glomerular hemodynamics via stimulating the production of prostaglandin E2 (PGE2) in the mesangial cells.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

技术参数 Specifications

species reactivity	rat
packaging	kit of 96 wells (12 strips x 8 wells)
technique(s)	ELISA: suitable,capture ELISA: suitable
input	sample type cell lysate sample type tissue lysate
assay range	inter-assay cv: <12% intra-assay cv: <10% sensitivity: 80 pg/mL standard curve range: 68.59-50000 pg/mL
detection method	colorimetric
shipped in	wet ice
storage temp.	−20°C
Gene Information	rat ... Il1b(24494)

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