- 商品介绍
- 规格参数
- 包装参数
General description
Immunoglobulin A (IgA) is the most abundant antibody isotype produced in humans. IgAs are heterogeneous and exist astwo IgA subtypes. It has the ability to form multimers by interacting with the joining (J) chain. It is present in large quantities in blood. Immunoglobulin A (IgA) antibodies protect mucosal surfaces against invading pathogens.
Application
IgA from human colostrum has been used to find out percent cross-selectivity values for lactoferrin immunosensors versus several common proteins contained in milk and saliva. It has also been used in western blotting.
IgA from human colostrum is a suitable ELISA standard used to estimate the concentrations of IgA in human B cell culture supernatants and in human blood, colostrum and cord blood samples.
Biochem/physiol Actions
IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears, colostrum and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces.
Physical form
Solution in 0.01 M Tris-HCl, 0.1 M sodium chloride, pH 8.0, containing 15 mM sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| conjugate | unconjugated |
| Quality Level | 300 |
| grade | reagent grade |
| form | buffered aqueous solution |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
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