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Protein Kinase A Inhibitor Fragment 6-22 amide，1MG，P6062-1MG，Sigma

销售价： ¥ 2239.63 / 件

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订货号： 0BM4314

品牌型号： Sigma P6062-1MG

货期：询货期

最小订货量： 1件

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商品介绍
规格参数
包装参数

产品介绍 Product Description

Application

Protein Kinase A Inhibitor Fragment 6-22 amide has been used as a PKA inhibitor:

to study its effects on oocytes in two-electrode voltage clamp (TEVC) experiments
to study its effects on antinociception levels in mice
in PKA phosphorylation assay

Biochem/physiol Actions

Protein Kinase A Inhibitor Fragment 6-22 amide (PKI 6-22) is a derivative of an active portion of the heat-stable cAMP-dependent protein kinase (PKA) inhibitor (PKI). It is a potent inhibitor of PKA.

Other Notes

Lyophilized from 0.1% TFA in H2O

技术参数 Specifications

Quality Level	200
assay	≥97% (HPLC)
form	powder
storage temp.	−20°C
SMILES string	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](N)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)O)C(N)=O
InChI	1S/C80H130N28O24/c1-10-37(3)60(63(83)118)106-66(121)41(7)96-72(127)52(32-55(81)113)103-69(124)49(22-17-29-92-80(88)89)100-68(123)47(20-15-27-90-78(84)85)98-57(115)35-94-76(131)62(43(9)111)108-70(125)48(21-16-28-91-79(86)87)99-56(114)34-93-67(122)54(36-109)105-65(120)40(6)97-77(132)61(38(4)11-2)107-74(129)51(30-44-18-13-12-14-19-44)102-73(128)53(33-58(116)117)101-64(119)39(5)95-71(126)50(104-75(130)59(82)42(8)110)31-45-23-25-46(112)26-24-45/h12-14,18-19,23-26,37-43,47-54,59-62,109-112H,10-11,15-17,20-22,27-36,82H2,1-9H3,(H2,81,113)(H2,83,118)(H,93,122)(H,94,131)(H,95,126)(H,96,127)(H,97,132)(H,98,115)(H,99,114)(H,100,123)(H,101,119)(H,102,128)(H,103,124)(H,104,130)(H,105,120)(H,106,121)(H,107,129)(H,108,125)(H,116,117)(H4,84,85,90)(H4,86,87,91)(H4,88,89,92)/t37-,38-,39-,40-,41-,42+,43+,47-,48-,49-,50-,51-,52-,53-,54-,59-,60-,61-,62-/m0/s1
InChI key	VAKHFAFLRUNHLQ-PEBJKXEYSA-N

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