- 商品介绍
- 规格参数
- 包装参数
General description
Methionine aminopeptidase from Pyrococcus furiosus is a 32 kDa thermostable enzyme. It belongs to type 2a class of methionine aminopeptidase. Methionine aminopeptidase maintains protein homeostasis and coordinates posttranslational modification of proteins in eukaryotes.
X-ray crystallography of the structure of methionine aminopeptidase from Pyrococcus furiosus or PfMAP was performed at a resolution of 1.75A and showed that the protein consists of a catalytic domain containing two cobalt ions in the active site and a unique insertion domain which is specific to the prokaryotic form of the protein.
Application
Methionine Aminopeptidase from Pyrococcus furiosus has been used in a study to analyze the binding of Co(II)-specific inhibitors to the methionyl aminopeptidases from Escherichia coli and Pyrococcus furiosus. It has also been used in a study to examine the binding of a new class of pseudopeptide analog inhibitors.
Biochem/physiol Actions
Thermostable methionine aminopeptidase, which specifically liberates the N-terminal methioinine from proteins and peptides.
Physical form
Solution containing 0.01% Tween® 20, 0.1 mM CoCl2, and 10 mM Tris-HCl, pH 7.5.
Other Notes
One unit will hydrolyze 1 μmol of Met from Met-Pro-Ala-Ala-Gly in 1 minute at pH 7.5 at 37 °C.
Legal Information
TWEEN is a registered trademark of Croda International PLC
| recombinant | expressed in E. coli |
| Quality Level | 200 |
| assay | ≥93% (SDS-PAGE) |
| form | solution |
| specific activity | 0.5 units/mg protein |
| mol wt | 37 kDa by SDS-PAGE |
| UniProt accession no. | P56218 |
| foreign activity | Other proteases, none detected |
| shipped in | dry ice |
| storage temp. | −20°C |
| Gene Information | Pyrococcus furiosus DSM 3638 ... PF0541(1468383) |
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¥ 3109.49
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¥ 4173.75
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmPES滤膜，孔径0.45um,适合瓶颈尺寸33mm，12/箱，295-3345，Nalgene，Thermofisher，赛默飞世尔¥ 1938.54
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¥ 2882.02
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¥ 1749.15
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¥ 5014.59
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¥ 4020.77
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