- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
SK33, a trifluoromethylated enobosarm analog, is a cell and brain penetrant, tissue selective and highly potent anti-androgen that reduces androgen receptor (AR) transcriptional activity. SK33 induces cell cycle arrest at G1 phase. It exhibits increased efficacy against acquired anti-androgen resistance prostate cancer cells.
cell and brain penetrant, tissue selective and highly potent anti-androgen that reduces androgen receptor (AR) transcriptional activity
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | OC(C(NC1=CC(C(F)(F)F)=C(C#N)C=C1)=O)(C)COC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2 |
| InChI | 1S/C20H13F9N2O3/c1-17(33,16(32)31-13-3-2-10(8-30)15(7-13)20(27,28)29)9-34-14-5-11(18(21,22)23)4-12(6-14)19(24,25)26/h2-7,33H,9H2,1H3,(H,31,32) |
| InChI key | VJIVKRQGSGBLFP-UHFFFAOYSA-N |
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¥ 2528.88
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¥ 1259.40
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¥ 2068.25
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¥ 1956.41
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¥ 3372.68
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¥ 3290.05
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¥ 1568.60
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¥ 1509.00
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¥ 8137.12
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¥ 4020.77
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¥ 787.34
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