- 商品介绍
- 规格参数
- 包装参数
General description
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5′ sequence and encoding distinct isoforms have been found for this gene.
Immunogen
A phospho specific peptide corresponding to residues surrounding S79 of human ACACA
Physical form
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Preparation Note
Store at -20℃. Avoid freeze / thaw cycles.
| biological source | rabbit |
| Quality Level | 100 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 257, 259, 265, 269 |
| species reactivity | human, rat, mouse |
| concentration | 1.61 mg/ml |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt accession no. | Q13085 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer79) |
| Gene Information | human ... ACACA(31) |
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| 重量(kg) |
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¥ 2528.88
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¥ 2622.09
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¥ 3109.49
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¥ 4039.86
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¥ 1724.25
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¥ 4390.38
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¥ 145427.01
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