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- 规格参数
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产品介绍
Product Description
Biochem/physiol Actions
Allosteric inhibitor of atypical PKC isoforms
PS432 is an allosteric inhibitor of Protein Kinase C (PKC) that targets regulatory site (PIF-pocket) present in the kinase domain. PS432 potently inhibits non-small cell lung cancer cells proliferation and tumor growth without side effects in a mouse xenograft model.
技术参数
Specifications
| assay | ≥98% (HPLC) |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| shipped in | ambient |
| storage temp. | 2-8°C |
| SMILES string | O=C1C(O)=C(C(OCC)=O)C(C2=CC=C(C3=CC=C(Cl)C=C3)O2)N1C4=NC(C=CC(C)=C5)=C5S4 |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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