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General description
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PDIA6 (Q15084).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IF/ICC
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| material | colorless |
| clone | 2Q1L1, monoclonal |
| form | liquid |
| mol wt | 54 kDa |
| species reactivity | human, rat |
| concentration | 2mg/mL |
| technique(s) | immunofluorescence: 1:50 - 1:200,western blot: 1:500 - 1:2000 |
| color | colorless |
| isotype | IgG |
| immunogen sequence | MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPT |
| UniProt accession no. | Q15084 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... PDIA6(10130) |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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¥ 1148.92
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¥ 2814.26
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¥ 6894.69
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¥ 2883.61
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¥ 1653.62
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¥ 4404.38
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¥ 8982.64
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¥ 1301.36
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¥ 1351.48
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