CD154-VioBright 515, human, REA238, 30 t,130-122-807,美天旎

销售价: ¥ 2837.43 / 件
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订货号 6JX8380
品牌型号 美天旎 130-122-807
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最小订货量 1件
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产品介绍 Product Description

Clone REA238 recognizes the human CD154 antigen, a 39 kDa transmembrane glycoprotein, also known as CD40L, gp39, T-BAM, TRAP, or Ly-62, which is a proinflammatory and prothrombotic ligand in the tumor necrosis factor family. CD154 is transiently up-regulated on activated CD4+ T cells and plays an important role as a costimulatory molecule in T cell/antigen-presenting cell interactions through ligation of CD40. It mediates B cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4.

Additional information: Clone REA238 displays negligible binding to Fc receptors.


Alternative names

CD40L, CD40-L, gp39, T-BAM, TRAP, Ly-62, HIGM1, IGM


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