- 商品介绍
- 规格参数
- 包装参数
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规格 |
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| Accession Number: | NP_005246 |
| Shipping Condition: | Dry Ice |
| Expression System: | Insect |
| Protein Form: | Recombinant, Catalytic |
| Validated Application: | Kinase Assay |
| Molecular Weight: | 70.2 kDa |
| KinaseFamily: | NAK Kinase Family |
| Protein Length: | aa 1 - 396 |
| Protein Tag: | GST Tag |
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储存 |
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| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
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描述 |
This GAK recombinant human protein (1–396) was expressed in insect cells. GAK serine/threonine kinase or Cyclin-G-associated kinase was originally identified as a protein that is associated with cyclin G. However, neither CDK5 nor GAK kinase activity is activated by cyclin G nor does GAK affect CDK5 kinase activity. GAK seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. GAK recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the LanthaScreen™ Eu Kinase Binding assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service
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| 重量(kg) |
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