Anti-BMP-7 Antibody, clone 2A10,100UG,MAB4350,Sigma

销售价: ¥ 5205.44 / 件
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订货号 0BW1623
品牌型号 Sigma MAB4350
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

46 kDa
Bone morphogenetic protein-7 (BMP-7), also known as osteogenic protein-1, is a member of the TGF- superfamily, and is widely expressed during embryonic development. Like other members of the bone morphogenetic protein family, BMP-7 works synergistically with BMP-2 to play a key role in the differentiation of mesenchymal cells into bone and cartilage tissues by actively recruiting stem cells from the surrounding tissue, thereby initiating the bone formation cascade. In adult cells, BMP-7 is predominately expressed in the brain, kidneys, and bladder.


Application

Immunohistochemistry: Recommended working dilution is 1:50.

Western Blotting: Recommended working concentration is 1 – 2 µg/mL.
This Anti-BMP-7 Antibody, clone 2A10 is validated for use in WB, IH for the detection of BMP-7.


Biochem/physiol Actions

Reactivity with other species has not been tested.


Physical form

Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4),
150 mM NaCl, and 0.05% sodium azide.


Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified antibody
antibody product typeprimary antibodies
clone2A10, monoclonal
species reactivitymouse, human
technique(s)immunohistochemistry: suitable,western blot: suitable
inputsample type mesenchymal stem cell(s)
isotypeIgG1κ
UniProt accession no.P18075
shipped inwet ice
target post-translational modificationunmodified
Gene Informationhuman ... BMP7(655)
mouse ... Bmp7(12162)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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