- 商品介绍
- 规格参数
- 包装参数
General description
100 kDa (Barclay, 1997)
CD10 is a 100 kDa protein belonging to a family of type II transmembrane metalloproteases which also includes the leukocyte antigens CD13, CD26, CD73 and aminopeptidase. The gene encoding CD10 is located on chromosome 3. CD10 is a zinc-dependent enzyme and is thought to down-regulate cellular responses to peptide hormones (Barclay, 1997). On lymphoid cells, CD10 is expressed on immature T and B precursor cells but is lost as the cells reach maturation. CD10 is, however, re-expressed on proliferating B cells and mature neutrophils (Jones, 1997). Anti-CD10, SS2/36, was included in the Third International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD 10 (Majdic, 1987).
Immunogen
Acute lymphoblastic leukemia cells
Application
Research Sub Category
Immunoglobulins & Immunology
Milli-Mark Anti-CD10-FITC Antibody, clone SS2/36 detects level of CD10 & has been published & validated for use in FC.
Research Category
Inflammation & Immunology
Biochem/physiol Actions
Antibody recognizes Human CD10 antigen.
Physical form
Protein A purified
Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Preparation Note
Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
Analysis Note
Control
PBMCs
Evaluated by flow cytometry using human PBMCs
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | FITC conjugate |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | SS2/36, monoclonal |
| species reactivity | human |
| manufacturer/tradename | Milli-Mark® |
| technique(s) | flow cytometry: suitable |
| isotype | IgG1κ |
| NCBI accession no. | NP_000893.2 |
| UniProt accession no. | P08473 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... MME(4311) |
| 长度(mm) | |
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