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General description
110/120/130 kDa Calculated
Deposits of amyloid protein in senile plaques near nerve processes are found in the brains of aged humand and cases of Alzheimer′s Disease. The principle component of this extracellular amyloid is beta A4, a 4 kDa peptide derived from a larger amyloid precursor protein (APP), which is widely expressed in the brain and body. The creation, transport and function of these proteins is currently an active area of research.
Immunogen
Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein.
Application
Anti-Alzheimer Precursor Protein A4 (N-terminus)-FITC Antibody, clone 22C11 detects level of Alzheimer Precursor Protein A4 (N-terminus) & has been published & validated for use in FC.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Biochem/physiol Actions
Antibody recognizes Alzheimer Precursor Protein
Physical form
Protein A purified
Purified mouse monoclonal IgG1 conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Preparation Note
Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.
Analysis Note
Control
B35 cells
Evaluated by flow cytometry using B35 cells
Legal Information
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | FITC conjugate |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 22C11, monoclonal |
| species reactivity | canine |
| manufacturer/tradename | Milli-Mark® |
| technique(s) | flow cytometry: suitable |
| isotype | IgG1 |
| NCBI accession no. | NP_000475 |
| UniProt accession no. | P05067 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... APP(351) |
| 长度(mm) | |
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