GP Antagonist-2A,1MG,371780-1MGCN,Sigma

销售价: ¥ 2139.49 / 件
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订货号 : 0BW0689
品牌型号 : Sigma 371780-1MGCN
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

A peptide that selectively inhibits the activation of Gq by M1-muscarinic cholinergic receptors. Also inhibits activation by cholecystokinin receptor in pancreatic acini at 10 µM. Blocks angiotensin II-stimulated sis-inducing factor and STAT3 tyrosine phosphorylation.


Biochem/physiol Actions

Cell permeable: no
Primary Target
Inhibits the activation of Gq by M1-muscarinic cholinergic receptors
Product does not compete with ATP.
Reversible: no


Other Notes

H-Arg-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH₂
Hunt, R.A., et al. 1999. Hypertension34, 603.
Tsunoda Y., et al. 1995. Biochem. Biophys. Res. Commun. 211, 648.
Mukai, H., et al. 1992. J. Biol. Chem.267, 16237.


Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Disclaimer

Toxicity: Standard Handling (A)


技术参数 Specifications
Quality Segment100
assay≥95% (HPLC)
formlyophilized solid
manufacturer/tradenameCalbiochem®
storage conditionOK to freeze
solubilitywater: 25 mg/mL
shipped inambient
storage temp.−20°C
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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