- 商品介绍
- 规格参数
- 包装参数
General description
A cell-permeable salicylic acid compound that acts as a highly potent, active-site directed and substrate competitive AKR1C1 inhibitor (Ki = 4 nM) with moderate to excellent selectivity over AKR1C2, AKR1C3 and AKR1C4 (Ki = 0.087, 4.2 and 18.2 µM, respectively). Shown to inhibit the metabolism of progesterone by AKR1C1 (IC50 = 460 nM in AKR1C1 overexpressing BAECs).
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
El-Kabbani, O., et al. 2011. J. Steroid Biochem. Mol. Biol.125, 105.
El-Kabbani, O., et al. 2009. J. Med. Chem.52, 3259.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
| Quality Segment | 100 |
| assay | ≥94% (HPLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,protect from light |
| color | white |
| solubility | DMSO: 50 mg/mL |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| SMILES string | OC1=C(C(O)=O)C=C(C2=CC=CC=C2)C=C1Br |
| InChI | 1S/C13H9BrO3/c14-11-7-9(8-4-2-1-3-5-8)6-10(12(11)15)13(16)17/h1-7,15H,(H,16,17) |
| InChI key | XVZSXNULHSIRCQ-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
¥ 1048.84
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 1153.44
-
¥ 1756.15
-
¥ 4110.85
-
询价
-
¥ 1152.81
-
¥ 1327.84
-
询价
-
¥ 619.92
-
¥ 462.77
-
¥ 2005.84
-
¥ 915.42
-
¥ 66743.99
微信小程序
7X24小时在线咨询