- 商品介绍
- 规格参数
- 包装参数
Application
M30 dihydrochloride may be used in monamine oxidase-mediated cell signaling studies.
Biochem/physiol Actions
M30 is a site-activated iron chelator and monoamine oxidase (MAO) inhibitor; with neuroprotective and anti-apoptotic activity. It is a multifunctional non-toxic, brain permeable iron chelator possessing a neuroprotective propargylamine moiety and an antioxidant-iron chelator moiety. M30 is a selective irreversible inhibitor of mitochondrial brain monoamine oxidases A and B (MAO-A and -B), providing for improved levels of neurotransmitters. It reduces oxidative damage and shows neuroprotective and neurorestorative effects in various neurodegenerative models of ALS, Alzheimer′s and Parkinson′s diseases, and is being investigated in other diseases where oxidative stress is a problem.
Site-activated iron chelator and monoamine oxidase (MAO) inhibitor; neuroprotective and anti-apoptotic
Features and Benefits
This compound is featured on the Dopamine and Norepinephrine Metabolism and Histamine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | green-yellow |
| solubility | DMSO, heptane and xylene: ≥21 mg/mL |
| storage temp. | 2-8°C |
| SMILES string | Cl.Cl.CN(CC#C)Cc1ccc(O)c2ncccc12 |
| InChI | 1S/C14H14N2O.2ClH/c1-3-9-16(2)10-11-6-7-13(17)14-12(11)5-4-8-15-14;;/h1,4-8,17H,9-10H2,2H3;2*1H |
| InChI key | XJNICPXVRPOSSO-UHFFFAOYSA-N |
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¥ 2528.88
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¥ 4164.19
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¥ 3109.49
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¥ 8293.41
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¥ 14407.09
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