- 商品介绍
- 规格参数
- 包装参数
General description
The Silencing mediator of retinoic acid & thyroid hormone receptor protein, commonly called the SMRT protein mediates the transcriptional repression of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription machinery. Consistent with this activity, this protein is known to form a large corepressor complex containing SIN3A/B and histone deacetylases HDAC1 and HDAC2. SMRT is also a component of the N-Cor repressor (nuclear receptor corepressor), a multi-subunit complex minimally composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A and GPS2. SMRT and nuclear receptor corepressor N-CoR are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity.
~ 275 kDa
Application
Use Anti-SMRT Antibody, clone 1SM-1E7 (Mouse Monoclonal Antibody) validated in WB to detect SMRT also known as CTG repeat protein 26, Silencing mediator of retinoic acid & thyroid hormone receptor.
Biochem/physiol Actions
This antibody recognizes SMRT.
Physical form
Unpurified mouse monoclonal IgG2aκ ascites with 0.05% sodium azide.
Analysis Note
Evaluated by Western Blot in human brain lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody detected SMRT on 10 µg of human brain lysate.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| clone | 1SM-1E7, monoclonal |
| species reactivity | mouse, rat, human |
| technique(s) | western blot: suitable |
| isotype | IgG2aκ |
| NCBI accession no. | NP_001070729.1 |
| UniProt accession no. | Q9Y618 |
| shipped in | dry ice |
| target post-translational modification | unmodified |
| Gene Information | human ... NCOR2(9612), TRAC(28755) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
¥ 4164.19
-
询价
-
询价
-
询价
-
询价
-
¥ 1956.41
-
瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmSFCA滤膜，孔径0.2um,适合瓶颈尺寸45mm，12/箱，291-4520，Nalgene，Thermofisher，赛默飞世尔¥ 2856.42
-
询价
-
¥ 3319.60
-
¥ 1509.00
-
¥ 1301.36
-
¥ 3852.13
-
¥ 8137.12
-
¥ 5061.38
-
¥ 2132.12
-
¥ 2099.27
-
¥ 3796.67
-
¥ 4614.63
-
¥ 2754.43
-
询价
微信小程序
7X24小时在线咨询