- 商品介绍
- 规格参数
- 包装参数
General description
A cell-permeable isoxazolyl-benzamide compound that is more effective than NSC23766 (Cat. Nos. 553502 & 553508) in inhibiting PDGF-BB- (Cat. No. 521225) induced cellular Rac1 activation (45.8% vs 11.1% inhibition by 4 h pretreatment of the respective compound at 50 µM) in serum-starved SMCs (human aortic smooth muscle cells) by interfering Rac1-Tiam1 interaction, while exhibiting no effect toward cellular Cdc42 and RhoA activation or Rac1 interaction to its effector Pak1. Shown to effectively prevent PDGF-BB-induced membrane ruffling and lamellipodia formation in serum-starved 3T3 cells (4 h pretreatment at 25 µM). Also available in InSolution
Packaging
Packaged under inert gas
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
| Quality Segment | 100 |
| assay | ≥93% (HPLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,protect from light |
| color | off-white |
| solubility | DMSO: 100 mg/mL |
| shipped in | ambient |
| storage temp. | 2-8°C |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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¥ 12156.68
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¥ 1148.92
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¥ 1573.49
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¥ 1779.22
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¥ 6330.00
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¥ 2883.61
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¥ 2842.54
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¥ 5014.59
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¥ 3896.11
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¥ 2099.27
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¥ 2888.88
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¥ 2754.43
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