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Calmodulin, His•Tag® Human, Recombinant，50UG，208670-50UGCN，Sigma

销售价： ¥ 2102.77 / 件

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订货号： 0BV9519

品牌型号： Sigma 208670-50UGCN

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最小订货量： 1件

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商品介绍
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产品介绍 Product Description

General description

Full-length, recombinant human calmodulin fused to a His•Tag sequence at the N-terminus. Contains four functional Ca²⁺-binding sites (aa 20-31; aa 56-67; aa 93-104; aa 129-140) with EF-hands (aa 7-42; aa 43-78; aa 80-115; aa 116-148); and a ubiquitination site at Lys²¹. This preparation is qualified for use as a substrate for protein tyrosine kinases in in vitro assays. Through its interaction with Ca²⁺, calmodulin mediates the control of a large number of enzymes, including protein kinases and phosphatases. It is expected to be phosphorylated at Thr⁴⁴ by CaMK4. In addition, it serves as a substrate for various protein tyrosine kinases.

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In PBS, 0.2% Protease Inhibitor Cocktail Set VII (Cat. No. 539138).

Preparation Note

Following initial thaw, aliquot and freeze (-70°C).

Other Notes

Chou, J.J., et al. 2001.Nat. Struct. Biol.8, 990.
Lennon, G., et al. 1996.Genomics33, 151.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

技术参数 Specifications

biological source	human
Quality Level	100
assay	>90% (SDS-PAGE)
form	liquid
manufacturer/tradename	Calbiochem^®
storage condition	OK to freeze,avoid repeated freeze/thaw cycles
shipped in	wet ice
storage temp.	−70°C

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