- 商品介绍
- 规格参数
- 包装参数
General description
Single chain vitamin K-dependent protein produced by osteoblasts. Osteocalcin purified from bovine bone. Binds to phospholipid vesicles in the presence of Ca2+ (Kd = 6 µM). Also binds hydroxylapatite. Possible role in bone mineralization, bone resorption, and bone formation. Note: Gla corresponds to γ-carboxyglutamic acid.
Physical form
In 75 mM NaCl, 10 mM sodium phosphate buffer, pH 7.4.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
Carter, S.D., et al. 1996. J. Anim. Sci. 74, 2719.
Watson, K.E., et al. 1994. J. Clin. Invest.93, 2106.
Tracy, R.P., et al. 1990. J. Bone Min. Res.5, 451.
Gendreau, M.A., et al. 1989. J. Biol. Chem.264, 6972.
H-Tyr-Leu-Asp-His-Trp-Leu-Gly-Ala-Pro-Ala-Pro-Tyr-Pro-Asp-Pro-Leu-Gla-Pro-Lys-Arg-Gla-Val-Cys²³-Gla-Leu-Asn-Pro-Asp-Cys²⁹-Asp-Glu-Leu-Ala-Asp-His-Ile-Gly-Phe-Gln-Glu-Ala-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val-OH (disulfide bond: 23 → 29)
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
| assay | ≥98% (SDS-PAGE) |
| Quality Level | 100 |
| form | liquid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,avoid repeated freeze/thaw cycles |
| pI | 4.0 - 4.5 |
| shipped in | wet ice |
| storage temp. | −20°C |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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