Anti-Thy-1 Antibody, clone M5/49,100UG,MABF34,Sigma

销售价: ¥ 2993.31 / 件
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订货号 0BV8433
品牌型号 Sigma MABF34
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Thy-1 membrane glycoprotein (Thy-1) is a glycosylphosphatidylinositol (GPI)-anchored surface protein belonging to the immunoglobulin superfamily and is a major cell surface protein found on both T–cells and in the brain. Thy-1 is thought to be involved in interactions taking place during synaptogenesis and other neurological events between cells or cells and their ligands. There are two known alleles for Thy-1; Thy1.1 and Thy1.2. Studies have shown N-glycosolation to take place at three locations on the protein.
~22 kDa observed.
Higher bands may be observed due to glycosylation.


Immunogen

B6 Anti-BNL4Φ lymphocytes


Application

Anti-Thy-1 Antibody, clone M5/49 detects level of Thy-1 & has been published & validated for use in WB.
Functional Assay: A previous lot of this antibody was used for the inhibition of B6 Anti-BNLΦ CTL mediated cell death. (Davignon, D., et al. (1981). PNAS USA. 78(7):4535-4539.)
Research Category
Inflammation & Immunology
Research Sub Category
Inflammation & Autoimmune Mechanisms

Neural Stem Cells


Physical form

Format: Purified
Protein G Purified
Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.


Preparation Note

Stable for 1 year at 2-8°C from date of receipt.


Analysis Note

Control
P388D1 cell lysate
Evaluated by Western Blot in P388D1 cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Thy-1 in 10 µg of P388D1 cell lysate.


Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcerat
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
cloneM549.4.1, monoclonal
species reactivitymouse
technique(s)western blot: suitable
isotypeIgG2aκ
NCBI accession no.NP_033408
UniProt accession no.P01831
shipped inwet ice
target post-translational modificationunmodified
Gene Informationhuman ... THY1(7070)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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