- 商品介绍
- 规格参数
- 包装参数
General description
Thy-1 membrane glycoprotein (Thy-1) is a glycosylphosphatidylinositol (GPI)-anchored surface protein belonging to the immunoglobulin superfamily and is a major cell surface protein found on both T–cells and in the brain. Thy-1 is thought to be involved in interactions taking place during synaptogenesis and other neurological events between cells or cells and their ligands. There are two known alleles for Thy-1; Thy1.1 and Thy1.2. Studies have shown N-glycosolation to take place at three locations on the protein.
~22 kDa observed.
Higher bands may be observed due to glycosylation.
Immunogen
B6 Anti-BNL4Φ lymphocytes
Application
Anti-Thy-1 Antibody, clone M5/49 detects level of Thy-1 & has been published & validated for use in WB.
Functional Assay: A previous lot of this antibody was used for the inhibition of B6 Anti-BNLΦ CTL mediated cell death. (Davignon, D., et al. (1981). PNAS USA. 78(7):4535-4539.)
Research Category
Inflammation & Immunology
Research Sub Category
Inflammation & Autoimmune Mechanisms
Neural Stem Cells
Physical form
Format: Purified
Protein G Purified
Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
P388D1 cell lysate
Evaluated by Western Blot in P388D1 cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Thy-1 in 10 µg of P388D1 cell lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rat |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | M549.4.1, monoclonal |
| species reactivity | mouse |
| technique(s) | western blot: suitable |
| isotype | IgG2aκ |
| NCBI accession no. | NP_033408 |
| UniProt accession no. | P01831 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... THY1(7070) |
| 长度(mm) | |
| 宽度(mm) | |
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