- 商品介绍
- 规格参数
- 包装参数
General description
A non-steroidal phytoestrogenic isoflavone found in soy-based food products. Has been shown to interact with human estrogen receptor with relatively low potency. Induces mammary gland proliferation in mice. Inhibits lecithin peroxidation induced by hydroxyl radicals. Also acts as a selective inhibitor of γ-isoform of alcohol dehydrogenase.
A phytoestrogenic isoflavone found in soy-based foods. Displays potent antioxidant properties and acts as a selective inhibitor of the γ-isoform of alcohol dehydrogenase. Shown to interact with human estrogen receptors with low potency. Induces mammary gland proliferation in mice.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Selective inhibitor of the γ-isoform of alcohol dehydrogenase
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Do not re-freeze any thawed aliquots.
Other Notes
Pool-Zobel, B.L., et al. 2000. Carcinogenesis 21, 1247.
Toda, S., and Shirataki, Y. 1999. Phytother. Res.13, 163.
Ruiz-Larrea, M.B., et al. 1997. Free Radic. Res.26, 63.
Keung, W.M. 1995. Biochem. Biophys. Res. Commun.215, 1137.
Wang, W., et al. 1995. Nutr. Cancer23, 131.
Miksicek, R.J. 1994. J. Steroid Biochem. Mol. Biol.49, 153.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
| Quality Segment | 100 |
| description | Merck USA index - 14, 4244 |
| assay | ≥90% (HPLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,protect from light |
| color | white to off-white |
| solubility | methanol: 2 mg/mL,DMSO: 200 mg/mL |
| shipped in | ambient |
| storage temp. | −20°C |
| SMILES string | O1c2c(ccc(c2)O)C(=O)C(=C1)c3ccc(cc3)OC |
| InChI | 1S/C16H12O4/c1-19-12-5-2-10(3-6-12)14-9-20-15-8-11(17)4-7-13(15)16(14)18/h2-9,17H,1H3 |
| InChI key | HKQYGTCOTHHOMP-UHFFFAOYSA-N |
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¥ 4173.75
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¥ 1724.25
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¥ 6330.00
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¥ 14407.09
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¥ 2151.46
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¥ 3335.66
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¥ 2307.00
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¥ 1156.91
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¥ 745.60
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¥ 67162.32
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