Anti-Integrin α1 Antibody, clone FB12, azide free,100UG,MAB1973Z,Sigma

销售价: ¥ 4981.47 / 件
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订货号 : 0BV7201
品牌型号 : Sigma MAB1973Z
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

130 kDa


Application

Detect Integrin α1 using this Anti-Integrin α1 Antibody, clone FB12, azide free validated for use in ELISA, FC, IH, IP, FUNC & WB.
Immunohistochemistry: 2 μg/mL, with paraformaldehyde fixation. Immunoblotting: 2 μg/mL

Immunoprecipitation: 1 μg/mL

FACS analysis: 2 μg/mL

ELISA: 0.5 μg/mL

Inhibition of activated human lymphocyte binding to laminin, collagen IV and fibronectin (Fabbri, 1996): 1-5 μg/mL

Optimal working dilutions must be determined by end user.


Biochem/physiol Actions

Reacts with the I domain (Val151 - Ala364) of human alpha1 integrin (Fabbri, 1996). Precipitates proteins of Mr 180 kDa, pI 5.9-6.0 (alpha chain) and Mr 115 kDa, pI 4.5-5.0 (beta chain) from human lymphocyte lysates (Zocchi, 1991). Does not recognize recombinant I domain of rat integrin alpha1.


Physical form

Format: Purified
Purified immunoglobulin in 0.02M PB, pH 7.6, 0.25M NaCl.


Analysis Note

Control
Microvascular endothelium


Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
cloneFB12, monoclonal
species reactivityhuman
manufacturer/tradenameChemicon®
technique(s)ELISA: suitable,flow cytometry: suitable,immunohistochemistry: suitable,immunoprecipitation (IP): suitable,western blot: suitable
isotypeIgG1
NCBI accession no.NM_181501.1
UniProt accession no.P56199
shipped inwet ice
target post-translational modificationunmodified
Gene Informationhuman ... ITGA1(3672)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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