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Anti-Protein Phosphatase 2 C α/β Antibody，100UG，07-1223，Sigma

销售价： ¥ 3105.69 / 件

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订货号： 0BV6543

品牌型号： Sigma 07-1223

货期：询货期

最小订货量： 1件

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商品介绍
规格参数
包装参数

产品介绍 Product Description

General description

Approx. 46 kDa
PP-2 C α/β is heterodimer located in the mitochondrial matrix. Within the pyruvate dehydrogenase complex, PP-2 C α/β serves to catalyze the dephosphorylation and concomitant reactivation of the E1 component’s alpha subunit. Mutations occurring in the PDP1 gene are the cause of a disease known as pyruvate dehydrogenase deficiency (PDP deficiency), which leads to neurological dysfunction from lactic acidosis.

Immunogen

Purified peptide conjugated to KLH.

Application

Detect Protein Phosphatase 2 C α/β using this Anti-Protein Phosphatase 2 C α/β Antibody validated for use in WB.
Research Category
Signaling
Research Sub Category
Kinases & Phosphatases

Biochem/physiol Actions

Recognizes the alpha/beta regulatory subunit isotype of protein phosphatase 2C (PP2C). PP 2C alpha/beta polyclonal antibody binds a 44-46 kDa protein.

Physical form

Format: Purified
Protein Purified
Purified immunoglobulin in phosphate buffered saline with 0.08% sodium azide.

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.

Analysis Note

Control
L6 Cell Lysate
Evaluated by Western Blot in L6 cell lysates.
Western Blot Analysis: 1:500 dilution of this lot detected PP-2 C ALPHA/BETA on 10 ug of L6 lysates.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: AB4090

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	rabbit
Quality Segment	100
conjugate	unconjugated
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	polyclonal
species reactivity	bovine, human, rat
species reactivity (predicted by homology)	mouse
technique(s)	western blot: suitable
UniProt accession no.	Q9P0J1
shipped in	wet ice
target post-translational modification	unmodified
Gene Information	human ... PDP1(54704)

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