- 商品介绍
- 规格参数
- 包装参数
General description
Plant alkaloid inhibitor of several β-glucosidases and α-glucosidases, including those involved in N-linked processing of glycoproteins. Resulting oligosaccharides are primarily Glu3Man7-9(GlcNAc)2. Reduces bFGF induced angiogenesis in mice. Inhibits endothelial cell migration and invasion of basement membrane. Exhibits anti-viral properties. Typically used at 1-10 µg/ml.
Biochem/physiol Actions
Cell permeable: no
Primary Target
β-glucosidases
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Ahmed, S.P., et al. 1995. Biochem. Biophys. Res. Commun. 208, 267.
Pili, R., et al. 1995. Cancer Res.55, 2920.
Walker, B.D., et al. 1987. Proc. Natl. Acad. Sci. USA84, 8120.
Pan, Y.T., et al. 1983. Biochemistry22, 3975.
Saul, R., et al. 1983. Arch. Biochem. Biophys. 221, 593.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
| description | Merck USA index - 14, 1896 |
| Quality Level | 100 |
| assay | ≥98% (TLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,desiccated (hygroscopic) |
| color | white |
| solubility | water: 1 mg/mL |
| shipped in | ambient |
| storage temp. | 2-8°C |
| SMILES string | N21[C@@H]([C@H]([C@@H]([C@H](C2)O)O)O)[C@H](CC1)O |
| InChI | 1S/C8H15NO4/c10-4-1-2-9-3-5(11)7(12)8(13)6(4)9/h4-8,10-13H,1-3H2/t4-,5-,6+,7+,8+/m0/s1 |
| InChI key | JDVVGAQPNNXQDW-TVNFTVLESA-N |
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