Castanospermine, Castanospermum australe,1MG,218775-1MGCN,Sigma

销售价: ¥ 1035.53 / 件
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订货号 0BV4243
品牌型号 Sigma 218775-1MGCN
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Plant alkaloid inhibitor of several β-glucosidases and α-glucosidases, including those involved in N-linked processing of glycoproteins. Resulting oligosaccharides are primarily Glu3Man7-9(GlcNAc)2. Reduces bFGF induced angiogenesis in mice. Inhibits endothelial cell migration and invasion of basement membrane. Exhibits anti-viral properties. Typically used at 1-10 µg/ml.


Biochem/physiol Actions

Cell permeable: no
Primary Target
β-glucosidases
Product does not compete with ATP.
Reversible: no


Packaging

Packaged under inert gas


Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.


Other Notes

Ahmed, S.P., et al. 1995. Biochem. Biophys. Res. Commun. 208, 267.
Pili, R., et al. 1995. Cancer Res.55, 2920.
Walker, B.D., et al. 1987. Proc. Natl. Acad. Sci. USA84, 8120.
Pan, Y.T., et al. 1983. Biochemistry22, 3975.
Saul, R., et al. 1983. Arch. Biochem. Biophys. 221, 593.


Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Disclaimer

Toxicity: Harmful (C)


技术参数 Specifications
descriptionMerck USA index - 14, 1896
Quality Level100
assay≥98% (TLC)
formsolid
manufacturer/tradenameCalbiochem®
storage conditionOK to freeze,desiccated (hygroscopic)
color white
solubilitywater: 1 mg/mL
shipped inambient
storage temp.2-8°C
SMILES stringN21[C@@H]([C@H]([C@@H]([C@H](C2)O)O)O)[C@H](CC1)O
InChI1S/C8H15NO4/c10-4-1-2-9-3-5(11)7(12)8(13)6(4)9/h4-8,10-13H,1-3H2/t4-,5-,6+,7+,8+/m0/s1
InChI keyJDVVGAQPNNXQDW-TVNFTVLESA-N
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高度(mm)
重量(kg)
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