Anti-Pro-Insulin C-Peptide Antibody, clone C-PEP-01,1MG,05-1109,Sigma

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订货号 : 0BV4118
品牌型号 : Sigma 05-1109
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

Approx. 12 kDa
Pro-Insulin consists of the three parts: C-peptide and two long strands of amino acids (alpha and beta chains; later become linked together to form the Insulin molecule). From every molecule of Pro-Insulin, one molecule of Insulin plus one molecule of C-peptide are produced. C-peptide is released into the blood stream in equal amounts to Insulin.


Immunogen

Synthetic C-peptide of human pro-insulin conjugated to bovine serum albumin.


Application

Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling
This Anti-Pro-Insulin C-Peptide Antibody, clone C-PEP-01 is validated for use in IH(P) for the detection of Pro-Insulin C-Peptide.


Biochem/physiol Actions

No cross-reactivity with Insulin or other peptide hormones or proteins was observed.
The antibody C-PEP-01 reacts specifically with C-peptide, a part of the Pro-insulin molecule.


Physical form

Format: Purified
Mouse monoclonal IgG1 in phosphate buffered saline, pH7.4, and 15 mM sodium azide.
Sequential precipitation with caprylic acid and ammonium sulfate.


Preparation Note

Store at 2-8°C and use within 1 year from date of receipt.


Analysis Note

Control
Human normal pancreas tissue
Evaluated by Immunohistochemistry in normal human pancreas.
Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected insulin in human normal pancreas tissue.


Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: CBL94


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
cloneC-PEP-01, monoclonal
species reactivityhuman
technique(s)immunohistochemistry: suitable (paraffin)
isotypeIgG1
UniProt accession no.P01308
shipped inwet ice
target post-translational modificationunmodified
Gene Informationhuman ... INS(3630)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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