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- 规格参数
- 包装参数
General description
A potent and selective inhibitor of poly(ADP-ribose) polymerase (PARP; IC50 = 40 nM). Significantly reduces infarcet volume in rat focual cerebrale ischemia model.
A very potent and selective poly(ADP-ribose)polymerase (PARP) inhibitor (IC50 = 40 nM). Significantly reduces infarcet volume in rat focual cerebrale ischemia model.
Biochem/physiol Actions
Cell permeable: no
Product does not compete with ATP.
Reversible: no
Other Notes
Eliasson, M.J., et al. 1997. Nat. Med. 3, 1089.
Takahashi, K., et al. 1997. J. Cereb. Blood Flow Metabl. 17, 1137.
Suto, M.J., et al. 1991. Anticancer Drug Des. 6, 107.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
| Quality Segment | 100 |
| assay | ≥90% (HPLC) |
| form | solid |
| potency | 40 nM IC50 |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze |
| color | off-white |
| solubility | DMSO: 5 mg/mL |
| shipped in | ambient |
| storage temp. | −20°C |
| SMILES string | N3(CCCCC3)CCCCOc1c2c(ccc1)C(=O)NCC2 |
| InChI | 1S/C18H26N2O2/c21-18-16-7-6-8-17(15(16)9-10-19-18)22-14-5-4-13-20-11-2-1-3-12-20/h6-8H,1-5,9-14H2,(H,19,21) |
| InChI key | RVOUDNBEIXGHJY-UHFFFAOYSA-N |
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| 重量(kg) |
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