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- 规格参数
- 包装参数
General description
CD138 is a transmembrane proteoglycan, bearing heparin sulphates and sometimes chondriotin sulfates. It consists of a 30.5 kDa core protein with 5 putative glycosaminoglycans attachment sites. CD138 is a member of the syndecan family. The reported Mr of CD138 ranges from 85,000 to 92,000, presumably depending on the glycosaminoglycan pattern of the molecule (Wijdenes, 1997). Within the hematopoietic system, CD138 is mainly confined to late stages of B-cell differentiation. It is typically expressed at high cellular density in plasma cells (Gattei, 1999). In mature tissues, CD138 is expressed by simple and stratified epithelia, fibroblasts, stratified keratinocytes and endothelial cells (Wijdenes, 1997). Anti-CD138, MI15, was included in the Sixth International Workshop and Conference on Human Leucocytes Differentiation Antigens, and studies by a number of different laboratories confirmed its reactivity with CD138 (Wijdenes, 1997).
85-92 kDa (Wijdenes, 1997)
Application
Detect CD138 using this Milli-Mark Anti-CD138-PE Antibody, clone MI15 validated for use in FC.
Biochem/physiol Actions
Antibody recognizes Human CD138 antigen
Analysis Note
Evaluated by flow cytometry using U266 cells
Legal Information
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | PE |
| antibody form | purified antibody |
| antibody product type | primary antibodies |
| clone | MI15, monoclonal |
| species reactivity | human |
| manufacturer/tradename | Milli-Mark® |
| technique(s) | flow cytometry: suitable |
| isotype | IgG1κ |
| NCBI accession no. | NP_001006947 |
| UniProt accession no. | P18827 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... SDC1(6382) |
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