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General description
Transcription factor HES-1 (HES-1) also known as Hairy and enhancer of split 1, Hairy homolog, Hairy-like protein, belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.
~30 kDa observed. Uncharacterized bands maybe observed in some lysates.
Immunogen
KLH-conjugated linear peptide corresponding to the near N-terminal of Mouse HES-1.
Application
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected HES-1 in mouse hindbrain, cerebellum and kidney tissue.
This Anti-HES-1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of HES-1.
Analysis Note
Evaluated by Western Blotting in mouse brain tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected Hes-1 in 10 µg of mouse liver tissue lysate.
Other Notes
Concentration: Please refer to lot specific datasheet.
Replaces: AB15470
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| purified by | affinity chromatography |
| species reactivity | mouse |
| species reactivity (predicted by homology) | human (based on 100% sequence homology), monkey (based on 100% sequence homology), hamster (based on 100% sequence homology), horse (based on 100% sequence homology), rat (based on 100% sequence homology) |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| NCBI accession no. | NP_032261 |
| UniProt accession no. | P35428 |
| shipped in | dry ice |
| target post-translational modification | unmodified |
| Gene Information | human ... HES1(3280) mouse ... Hes1(15205) |
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¥ 1563.36
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¥ 2019.57
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¥ 1779.22
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¥ 2068.25
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¥ 2883.61
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