Lipoxin A₄,25UG,437720-25UGCN,Sigma

销售价: ¥ 4179.87 / 件
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订货号 0BV2990
品牌型号 Sigma 437720-25UGCN
货期 询货期
最小订货量 1件
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  • 商品介绍
  • 规格参数
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产品介绍 Product Description

General description

Caution! Product contains volatile liquid. Keep product cold at all times.
Potent inhibitor of cytotoxic activity of human natural killer cells; shown to be as potent as LTB4 in stimulating human neutrophils to generate superoxides. Involved in contractile responses and acts as a potent activator of human protein kinase C. Stimulates rapid lipid remodeling and pertussis-sensitive release of arachidonic acid in polymorphonuclear leukocytes. Stimulates MAP kinases via activation of G protein-coupled receptors.


Biochem/physiol Actions

Cell permeable: no
Primary Target
Potent inhibitor of cytotoxic activity of human natural killer cells
Product does not compete with ATP.
Reversible: no


Physical form

In Ethanol.


Preparation Note

Following initial thaw, aliquot and freeze (-70°C).


Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
McMahon, B., et al. 2000. J. Biol. Chem. 275, 27566.
Soyombo, O., et al. 1994. Allergy 49, 230.
Flore, S., et al. 1992. J. Biol. Chem.267, 16168.
Badr, K.F., et al. 1989. Proc. Natl. Acad. Sci. USA86, 3438.


Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Disclaimer

Toxicity: Flammable (J)


技术参数 Specifications
Quality Level100
assay≥95% (HPLC)
formliquid
manufacturer/tradenameCalbiochem®
storage conditionOK to freeze
solubilityethanol: soluble
shipped inwet ice
storage temp.−70°C
SMILES stringO[C@H]([C@H](O)\C=C\C=C\C=C/C=C/[C@@H](O)CCCCC)CCCC(=O)O
InChI1S/C20H32O5/c1-2-3-8-12-17(21)13-9-6-4-5-7-10-14-18(22)19(23)15-11-16-20(24)25/h4-7,9-10,13-14,17-19,21-23H,2-3,8,11-12,15-16H2,1H3,(H,24,25)/b6-4-,7-5+,13-9+,14-10+/t17-,18+,19-/m0/s1
InChI keyIXAQOQZEOGMIQS-SSQFXEBMSA-N
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