首页> 生物试剂> 其他生物试剂> 其他> Anti-Human IgM (μ-chain specific) antibody, Mouse monoclonal，100UL，SAB4200780-100UL，Sigma

收藏产品

Anti-Human IgM (μ-chain specific) antibody, Mouse monoclonal，100UL，SAB4200780-100UL，Sigma

销售价： ¥ 7019.06 / 件

在线询价

优惠：请询价

订货号： 0BV0771

品牌型号： Sigma SAB4200780-100UL

货期：询货期

最小订货量： 1件

+ -

加入购物车

联系我们

400-920-3909

微信扫一扫，手机采购

精选商品

胰蛋白胨，500g，LP0042B，Oxoid

销售价：询价

加入购物车

商品介绍
规格参数
包装参数

产品介绍 Product Description

General description

Anti-Human IgM (m-chain specific) antibody, Mouse monoclonal (mouse IgG2b isotype) is derived from the MB-11 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from a mouse immunized with purified human IgM protein.
Immunoglobulin M (IgM) is the major class of surface immunoglobulins on lymphocyte membranes. IgM is suggested to act as the first line of defense during microbial infections. IgM has a pentameric structure, in which monomers are linking together via disulfide bonds. Surface IgM is expressed on immature and mature B cells, whereas IgM heavy chain is expressed intracellularly in pre-B cells. IgM serves as the antigen receptor of naive B cells and is involved in B cell maturation and complement activation.

Immunogen

Purified human IgM

Application

The antibody is recommended to use in various immunological techniques, including ELISA and Immunoblot.

Biochem/physiol Actions

Anti-Human IgM (m-chain specific) antibody, Mouse monoclonal specifically recognizes m chain of Human IgM. The antibody shows no cross-reactivity with human IgG, Fab, Fc, k, l, and g chains.
Immunoglobulin M (IgM) acts as an antigen specific part of the B cell antigen receptor on the surface of B lymphocytes that are not stimulated, in its monomeric form. Polymeric IgM molecules also serve as important activators of the classical complement cascade. IgM is essential in agglutination and cytolytic reactions. IgM serves as the antigen receptor of naive B cells and is involved in B cell maturation and complement activation.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as a preservative.

Other Notes

This product is for R&D use only, not for drug, household, or other uses.

技术参数 Specifications

biological source	mouse
Quality Level	300
antibody form	purified from hybridoma cell culture
antibody product type	primary antibodies
clone	MB-11, monoclonal
form	buffered aqueous solution
species reactivity	human
concentration	~1.0 mg/mL
technique(s)	ELISA: 0.1-0.2 μg/mL using 2.5 μg/mL Human IgM myeloma for coating,immunoblotting: suitable
isotype	IgG2b
shipped in	dry ice
storage temp.	−20°C
target post-translational modification	unmodified

长度(mm)
宽度(mm)
高度(mm)
重量(kg)