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- 规格参数
- 包装参数
Biochem/physiol Actions
Ibufenac is a non-steroidal anti-inflammatory drug (NSAID) analog of ibuprofen that was withdrawn for hepatotoxicity. It inhibits cyclooxygenases COX-1 and -2 activity with IC50 values of 17.4 and 13.1 μM, respectively and > 40 μM for 5-LOX. It has been used in studies of drug-induced hepatotoxicity.
Non-steroidal anti-inflammatory drug (NSAID) analog of ibuprofen, cyclooxygenase inhibitor withdrawn for hepatotoxicity
| Quality Segment | 100 |
| assay | ≥95% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | −20°C |
| SMILES string | OC(CC1=CC=C(CC(C)C)C=C1)=O |
| InChI | 1S/C12H16O2/c1-9(2)7-10-3-5-11(6-4-10)8-12(13)14/h3-6,9H,7-8H2,1-2H3,(H,13,14) |
| InChI key | CYWFCPPBTWOZSF-UHFFFAOYSA-N |
| Gene Information | human ... PTGS1(5742), PTGS2(5743) |
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