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General description
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 70-150 of human RAIDD/CRADD (P78560).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IHC
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| material | colorless |
| clone | 7M7M6, monoclonal |
| form | liquid |
| mol wt | 23 kDa |
| species reactivity | rat, human |
| concentration | 0.13 mg/mL |
| technique(s) | immunohistochemistry: 1:50 - 1:200,western blot: 1:500 - 1:2000 |
| color | colorless |
| isotype | IgG |
| immunogen sequence | DTFLDSLQEFPWVREKLKKAREEAMTDLPAGDRLTGIPSHILNSSPSDRQINQLAQRLGPEWEPMVLSLGLSQTDIYRCKA |
| UniProt accession no. | P78560 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... CRADD(8738) |
| 长度(mm) | |
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| 重量(kg) |
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¥ 2814.26
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¥ 1779.22
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¥ 9207.92
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¥ 3275.78
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¥ 10277.12
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¥ 1196.00
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¥ 4476.05
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