CYM-5520,5MG,SML1014-5MG,Sigma

销售价: ¥ 1072.00 / 件
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订货号 0BU6754
品牌型号 Sigma SML1014-5MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Application

CYM-5520 has been used as a sphingosine 1-phosphate receptor 2 (S1pr2) agonist in pancreatic adenocarcinoma cell line (CFPAC-1).


Biochem/physiol Actions

CYM-5520 mediates phosphorylation of transcription factor p65. It upregulates trabecular number, thickness as well as tibial bone volume density in osteoblasts.
CYM-5520 is a specific, noncompetitive allosteric agonist of sphingosine 1-phosphate receptor 2 (S1PR2; EC50 = 1.0 μM). The compound CYM-5520 does not show any agonsit activity towards S1PR1, S1PR3, S1PR4 or S1PR5.
CYM-5520 is a specific, noncompetitive allosteric agonist of sphingosine 1-phosphate receptor 2.


技术参数 Specifications
Quality Segment100
assay≥98% (HPLC)
formpowder
color white to beige
solubilityDMSO: 20 mg/mL, clear
storage temp.2-8°C
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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