环苯扎林 盐酸盐,5G,C4542-5G,Sigma

销售价: ¥ 5781.81 / 件
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订货号 : 0BU6730
品牌型号 : Sigma C4542-5G
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

Cyclobenzaprine is a tricyclic agent, which has anti-depressant and anti-cholinergic properties. It lowers the tonic somatic motor activity of motor neuron systems. Cyclobenzaprine prevents the uptake of noradrenaline. It is used to treat neck, back and myofascial pain. Cyclobenzaprine functions as a nerve impulse inhibitor.


Application

Cyclobenzaprine hydrochloride has been used to study its effect on the muscles of dystrophin-deficient mdx5Cv mice.
Cyclobenzaprine hydrochloride has been used to study its effects on the muscles of dystrophin-deficient mdx5Cv mice.


Biochem/physiol Actions

Cyclobenzaprine hydrochloride is a type of tricyclic skeletal drug, which is commonly used as a muscle relaxant. It is very effective in treating intractable pain of cervical and lumbar origin caused by skeletal muscle spasm. cyclobenzaprine hydrochloride inhibit tonic α-mononeuronal excitation mediated by descending serotonergic systems by interacting with serotonin receptors at the spinal cord level.
Skeletal muscle relaxant; 5-HT2 serotonin receptor antagonist.
Skeletal muscle relaxant; reduces muscle spasm by depression of brainstem neurons; 5-HT2 serotonin receptor antagonist.


Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


技术参数 Specifications
formpowder
Quality Segment200
originatorJohnson & Johnson
SMILES stringCl.CN(C)CC\C=C1\c2ccccc2C=Cc3ccccc13
InChI1S/C20H21N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-14H,7,15H2,1-2H3;1H
InChI keyVXEAYBOGHINOKW-UHFFFAOYSA-N
Gene Informationhuman ... HTR2A(3356), HTR2B(3357), HTR2C(3358)
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