Monoclonal Anti-GM2A, (C-terminal) antibody produced in mouse，100UG，SAB1402791-100UG，Sigma

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订货号： 0BU6552

品牌型号： Sigma SAB1402791-100UG

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最小订货量： 1件

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产品介绍 Product Description

General description

This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. (provided by RefSeq)

Immunogen

GM2A (NP_000396.2, 94 a.a. ~ 193 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
WIKIPCTDYIGSCTFEHFCDVLDMLIPTGEPCPEPLRTYGLPCHCPFKEGTYSLPKSEFVVPDLELPSWLTTGNYRIESVLSSSGKRLGCIKIAASLKGI

Physical form

Solution in phosphate buffered saline, pH 7.4

技术参数 Specifications

biological source	mouse
Quality Segment	100
conjugate	unconjugated
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	2C8, monoclonal
form	buffered aqueous solution
mol wt	antigen ~37.11 kDa
species reactivity	human
technique(s)	capture ELISA: suitable,indirect ELISA: suitable
isotype	IgG2bκ
NCBI accession no.	NM_000405
UniProt accession no.	P17900
shipped in	dry ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... GM2A(2760)

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