- 商品介绍
- 规格参数
- 包装参数
General description
PA2G4 codes for an RNA-binding protein that modulates growth. It is homologous to the mouse cell cycle protein p38-2G4. PA2G4 may be involved in eukaryotic DNA replication and ErbB-3-mediated signaling pathways.
Rabbit Anti-PA2G4 antibody recognizes human, mouse, rat, canine, bovine, and zebrafish PA2G4.
Immunogen
Synthetic peptide directed towards the C terminal region of human PA2G4
Application
Rabbit Anti-PA2G4 antibody is suitable for western blot applications at a concentration of 1μg/ml.
Biochem/physiol Actions
PA2G4 is an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells.This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: LLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQ
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 44 kDa |
| species reactivity | rat, guinea pig, bovine, rabbit, human, dog, horse, mouse |
| concentration | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| web metadata keyword.default | 2,6-dimethyl-4-propoxybenzamide CAS number,2,6-dimethyl-4-propoxybenzamide Sigma-Aldrich,2,6-dimethyl-4-propoxybenzamide application in drug development,2,6-dimethyl-4-propoxybenzamide chemical,2,6-dimethyl-4-propoxybenzamide for pharmaceutical research,2,6-dimethyl-4-propoxybenzamide in,2,6-dimethyl-4-propoxybenzamide product data sheet,2,6-dimethyl-4-propoxybenzamide reagent for organic synthesis,2,6-dimethyl-4-propoxybenzamide research grade,2,6-dimethyl-4-propoxybenzamide,high-purity 2,6-dimethyl-4-propoxybenzamide,laboratory-grade 2,6-dimethyl-4-propoxybenzamide,sourcing 2,6-dimethyl-4-propoxybenzamide for lab use |
| NCBI accession no. | NP_006182 |
| UniProt accession no. | Q9UQ80 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... PA2G4(5036) |
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