Anti-phospho-RAD51 (pTyr³¹⁵) antibody produced in rabbit,100UG,SAB4504264-100UG,Sigma

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订货号 0BU5301
品牌型号 Sigma SAB4504264-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

RAD51 (RAD51 recombinase) belongs to the RecA/RadA/Rad51 protein family. It has a conserved ATP binding core. This protein is expressed in testis, ovary, and lymphoid tissue. It is located on human chromosome 15q15.


Immunogen

The antiserum was produced against synthesized peptide derived from human RAD51 around the phosphorylation site of Tyr315.

Immunogen Range: 281-330


Application

Anti-phospho-RAD51 (pTyr315) antibody has been used in western blotting.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)


Biochem/physiol Actions

RAD51 (RAD51 recombinase) plays a major role in homology-directed repair (HDR) and cell viability.This gene acts an an important target for cancer therapy. RAD51 interacts with BRCA2 (breast cancer susceptibility protein) and participates in DSB (double strand DNA breaks) repair.


Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.


Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wtantigen 36 kDa
species reactivityrat, human, mouse
concentration~1 mg/mL
technique(s)ELISA: 1:10000,western blot: 1:500-1:1000
NCBI accession no.Q06609
UniProt accession no.Q06609
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pTyr315)
Gene Informationhuman ... RAD51(5888)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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