- 商品介绍
- 规格参数
- 包装参数
Application
β-Muricholic Acid has been used as a bile acid to study its effects on the expression of pluripotency, stemness, and inflammatory genes in primary mouse hepatocytes (PMH) and tumor-initiating stem-like cells(TICs). It has also been used as a bile acid to study its effects on gut transit ingnotobiotic or conventional mouse models.
Biochem/physiol Actions
β-Muricholic Acid is a naturally occurring trihydroxy hydrophilic bile acid that is produced in the liver of murine. It serves as a biliary cholesterol-desaturating agent and aids in the dissolution of cholesterol gallstones.
β-Muricholic acid (β-MCA) is a natural murine-specific bile acid. β-Muricholic acid has been shown to reduce the absorption of cholesterol. It also has some activity as a farnesoid X receptor antagonist.
Murine-specific bile acid, farnesoid X receptor antagonist
| assay | ≥98% (HPLC) |
| form | powder |
| optical activity | [α]/D +59 to +65°, c = 0.5 in methanol |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | −20°C |
| SMILES string | O[C@H]1[C@H]2[C@@](C3C([C@H]1O)C4[C@@](C(CC4)C(CCC(=O)O)C)(CC3)C)(CC[C@H](C2)O)C |
| InChI | 1S/C24H40O5/c1-13(4-7-19(26)27)15-5-6-16-20-17(9-11-23(15,16)2)24(3)10-8-14(25)12-18(24)21(28)22(20)29/h13-18,20-22,25,28-29H,4-12H2,1-3H3,(H,26,27)/t13?,14-,15?,16?,17?,18+,20?,21+,22-,23-,24-/m1/s1 |
| InChI key | DKPMWHFRUGMUKF-CWNVCPLQSA-N |
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¥ 2622.09
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¥ 1573.49
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¥ 2013.69
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¥ 3109.49
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¥ 9737.84
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¥ 3275.78
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¥ 14407.09
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¥ 10277.12
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¥ 2307.00
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¥ 3476.87
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