IgG1,κ 来源于鼠骨髓瘤,5MG,M1398-5MG,Sigma

销售价: ¥ 4228.54 / 件
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订货号 0BU3913
品牌型号 Sigma M1398-5MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The MOPC 31C tumor line that produces mouse IgG1,k is a mineral oil-induced plasmacytoma originated and carried subcutaneously in BALB/c mice. Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3.


Application

IgG1, Kappa from murine myeloma has been used in immunohistochemistry.


Biochem/physiol Actions

Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. IgG2a has cytotropic properties and IgG2 molecules have the ability to activate the complement system. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.
IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. It provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.


Preparation Note

Reconstitute with 1 ml deionized water.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Level200
conjugateunconjugated
antibody formascites fluid
cloneMOPC 31C, monoclonal
formlyophilized powder
storage temp.2-8°C
target post-translational modificationunmodified
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