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General description
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5′ alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 30-238 of human F11R (NP_058642.1).
Physical form
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Preparation Note
Store at -20℃. Avoid freeze / thaw cycles.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 27, 32 |
| species reactivity | rat, human, mouse |
| concentration | 6.01 mg/ml |
| technique(s) | immunofluorescence: 1:50-1:200,immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000 |
| UniProt accession no. | Q9Y624 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... F11R(50848) |
| 长度(mm) | |
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| 重量(kg) |
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¥ 673.51
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¥ 1615.94
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¥ 2355.14
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¥ 5762.83
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¥ 8152.33
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¥ 462.77
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¥ 634.68
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¥ 70526.15
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