RyR1-selective inhibitor 1,5MG,SML3308-5MG,Sigma

销售价: ¥ 949.58 / 件
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订货号 0BU1258
品牌型号 Sigma SML3308-5MG
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最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

Potent and selective inhibitor of the type 1 ryanodine receptor (RyR1)
RyR1-selective inhibitor 1 (6,7-(methylenedioxy)-1-octyl-4-quinolone-3-carboxylic acid) potently and selectively inhibits the type 1 ryanodine receptor (RyR1). It prevents and treats malignant hyperthermia and heat stroke in several mouse models. RyR1-selective inhibitor 1 decreases resting intracellular Ca2+, inhibits halothane- and isoflurane-induced Ca2+ release, and suppresses caffeine-induced contracture in skeletal muscle.


技术参数 Specifications
Quality Segment100
assay≥98% (HPLC)
formpowder
storage conditiondesiccated
color white to beige
solubilityH2O: 2 mg/mL, clear (Warmed)
storage temp.room temp
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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