- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
BC-2059 is a cell penetrant, potent and selective inhibitor of the Wnt-signaling pathway that potently inhibits growth of cancer cell lines in vitro. BC-2059 inhibits β-catenin/transducin β-like 1 (TBL1) complex by direct binding to TBL1 complexed with β-catenin. BC-2059 does not inhibit interaction of TBL1 with either NCoR/SMRT or NFkB. It is a potential therapeutic for tumors with deregulated Wnt signaling pathway.
cell penetrant, potent and selective inhibitor of the Wnt-signaling pathway; inhibitor of β-catenin/TBL1 complex
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | −20°C |
| SMILES string | [S](=O)(=O)(N5C[C@H](C[C@H](C5)C)C)c1cc2c(cc1)C(c3c(cc(cc3)[S](=O)(=O)N4C[C@H](C[C@H](C4)C)C)C2N=O)N=O |
| InChI | 1S/C28H36N4O6S2/c1-17-9-18(2)14-31(13-17)39(35,36)21-5-7-23-25(11-21)28(30-34)26-12-22(6-8-24(26)27(23)29-33)40(37,38)32-15-19(3)10-20(4)16-32/h5-8,11-12,17-20,27-28H,9-10,13-16H2,1-4H3/t17-,18+,19-,20+,27?,28? |
| InChI key | LQQUOMJXUXVPRB-IOTKHNBZSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
询价
-
¥ 2013.69
-
¥ 9207.92
-
询价
-
询价
-
¥ 3275.78
-
询价
-
询价
-
¥ 4968.78
-
¥ 3290.05
-
询价
-
¥ 2151.46
-
¥ 1301.36
-
¥ 8137.12
-
¥ 3476.87
-
¥ 954.17
-
¥ 9909.51
-
¥ 56581.65
-
¥ 44224.19
微信小程序
7X24小时在线咨询