首页> 化学试剂> 其他化学试剂> 其他> GSK3787，5MG，G7423-5MG，Sigma

收藏产品

GSK3787，5MG，G7423-5MG，Sigma

销售价： ¥ 1352.43 / 件

在线询价

优惠：请询价

订货号： 0BU0770

品牌型号： Sigma G7423-5MG

货期：询货期

最小订货量： 1件

+ -

加入购物车

联系我们

400-920-3909

微信扫一扫，手机采购

精选商品

ITS液体培养基补充剂（100x），I3146-5ML，Sigma

销售价： ¥ 732.26

加入购物车

LookOut DNA Erase，250 mL，L8917-250ML

销售价： ¥ 694.95

加入购物车

F-12培养基,N4888-6X500ML,Sigma

销售价： ¥ 2452.59

加入购物车

潮霉素B，20ML，10843555001，Roche

销售价： ¥ 2657.23

加入购物车

NADPH，1G，10621706001，Roche

销售价： ¥ 28614.04

加入购物车

光溜海绵素C，10UG，X2628-10UG，Sigma

销售价： ¥ 5069.97

加入购物车

商品介绍
规格参数
包装参数

产品介绍 Product Description

Application

GSK3787 has been used to inhibit the role of peroxisome proliferator-activated receptor-delta (PPARδ), during the pre-implantation period of bovine embryonic development. It has also been used as a PPARδ-specific inhibitor in in vitro maturation (IVM) media to inhibit PPARδ.

Biochem/physiol Actions

GSK3787 is an orally available selective irreversible Peroxisome Proliferator-Activated Receptor δ (PPARδ) antagonist (pIC50=6.6) with no measurable affinity for hPPARR or hPPARγ (pIC50<5).
GSK3787 is an orally available selective irreversible Peroxisome Proliferator-Activated Receptor δ (PPARδ) antagonist (pIC50=6.6) with no measurable affinity for hPPARR or hPPARγ (pIC50<5). It acts by covalently modifying Cys249 within the ligand binding pocket, and has been shown to antagonize the induction of PPARδ-regulated target genes in skeletal muscle cells.
GSK3787 is known to exhibit pharmacokinetic properties.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

技术参数 Specifications

assay	≥98% (HPLC)
form	powder
storage condition	desiccated
color	white to off-white
solubility	DMSO: ≥10 mg/mL
originator	GlaxoSmithKline
storage temp.	2-8°C
SMILES string	O=S(C1=CC=C(C=N1)C(F)(F)F)(CCNC(C2=CC=C(Cl)C=C2)=O)=O
InChI	1S/C15H12ClF3N2O3S/c16-12-4-1-10(2-5-12)14(22)20-7-8-25(23,24)13-6-3-11(9-21-13)15(17,18)19/h1-6,9H,7-8H2,(H,20,22)
InChI key	JFUIMTGOQCQTPF-UHFFFAOYSA-N

长度(mm)
宽度(mm)
高度(mm)
重量(kg)